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patenting genes

Reversing a longstanding policy, the federal government said on Friday that human and other genes should not be eligible for patents because they are part of nature. The new position could have a huge impact on medicine and on the biotechnology industry.

via NYTimes.com.

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The issue of gene patents has long been a controversial and emotional one. Opponents say that genes are products of nature, not inventions, and should be the common heritage of mankind. They say that locking up basic genetic information in patents actually impedes medical progress. Proponents say genes isolated from the body are chemicals that are different from those found in the body and therefore are eligible for patents.

The Patent and Trademark Office has sided with the proponents and has issued thousands of patents on genes of various organisms, including on an estimated 20 percent of human genes.

But in its brief, the government said it now believed that the mere isolation of a gene, without further alteration or manipulation, does not change its nature.

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smart drugs

I felt burned out after a series of long foreign assignments, and my brain was rustily chug-chugging along at half-speed. That's when I first read about a drug being billed as "Viagra for the brain" – not Ritalin, but Provigil, a brand name for modafinil. It was originally designed for narcoleptics, but clinical trials stumbled across something odd: if you give it to non-narcoleptics, they become smarter. Their memory and concentration improves considerably, and so does their IQ. There were no known side-effects, except – oh, thank you! – weight loss.

I hunted it down online. A week later, the little white pills arrived in the post. Within a few hours of a 200mg dose, I found myself gliding into a state of long, deep concentration, able to read a book for six or seven hours at a time without looking up. My mood wasn't any different; I wasn't high. It was like I had opened a window in my brain and all the stuffy air had seeped out, to be replaced by a calm breeze. On Provigil, I had the most productive month of my life, writing reams of articles. I didn't notice any side-effects – until the third week.

via Johann Hari.

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this is not immortality

There's something so deeply wrong about this article's perspective:

Brooke's sisters are named Emily, Caitlin and Carly. Brooke is the second youngest. She will be 18 in January.

Other girls her age are driving, going out dancing and sleeping with their first boyfriends. But for Brooke it's as if time had stood still. Mentally and physically, the girl remains at the level of an 11-month-old baby.

"Brooke is a miracle," says her father, Howard Greenberg. "Brooke is a mystery," says Lawrence Pakula, her pediatrician. "Brooke is an opportunity," says Richard Walker, a geneticist with the University of South Florida College of Medicine. They all mean the girl from Reisterstown, a small town in the US state of Maryland, who may hold the answer to a human mystery. At issue is nothing less than immortality: Brooke Greenberg apparently isn't aging.

She has no hormonal problems, and her chromosomes seem normal. But her development is proceeding "extremely slowly," says Walker. If scientists can figure out what is causing the disorder, it might be possible to unlock the mysteries of aging itself. "Then we've got the golden ring," says Walker.

He hopes to simply eliminate age-related diseases like cancer, dementia and diabetes. People who no longer age will no longer get sick, he reasons. But he also thinks eternal life is conceivable. "Biological immortality is possible," says Walker. "If you don't get hit by a car or by lightning, you could live at least 1,000 years."

via SPIEGEL ONLINE.

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seriously?

Students and professors at the University of Manitoba are rallying around a math professor who has been suspended for three months without pay after he took legal action to overturn the university's decision to award a PhD to a student who hadn't met all the requirements. Gábor Lukács said the U of M is demeaning the reputation of other PhD students and the professors who teach them. "The shadow of suspicion that the present case casts on all other, hard-working students who did fulfil their requirements bothers me a lot," Lukács said.

"The hard-working students who toil for years to earn their PhDs deserve better than this."

Lukács said the U of M awarded a PhD in mathematics in October to an individual who lacked the academic requirements, who failed a critical exam twice, and was then informed he didn't have to take the exam.

via Winnipeg Free Press.

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ipad therapy

OWEN CAIN depends on a respirator and struggles to make even the slightest movements — he has had a debilitating motor-neuron disease since infancy. Owen, 7, does not have the strength to maneuver a computer mouse, but when a nurse propped her boyfriend’s iPad within reach in June, he did something his mother had never seen before.

He aimed his left pointer finger at an icon on the screen, touched it — just barely — and opened the application Gravitarium, which plays music as users create landscapes of stars on the screen. Over the years, Owen’s parents had tried several computerized communications contraptions to give him an escape from his disability, but the iPad was the first that worked on the first try.

via NYTimes.com.

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brutal grace

A thoughtful piece:

Throughout much of her life, Flannery O'Connor struggled against what she perceived as dangerous and excessive sentimentality among her readers, defending her stories against accusations of violence, brutality, and "gothic grotesqueness." For her, violence was an essential part of her message, for "to expect too much is to have a sentimental view of life and this is a softness that ends in bitterness." Responding to her critics, O'Connor made an important point: "Our age not only does not have a very sharp eye for the almost imperceptible intrusions of grace, it no longer has much feeling for the nature of the violences which precede and follow them."

via patheos.com

One modern-day artist making that connection may be Cormac McCarthy, the reclusive author who is considered by many to be America's greatest living writer. A closer examination of the three cinematic adaptations based on his books -- All the Pretty Horses, No Country for Old Men, and The Road -- reveals him to be as focused on the questions of nature, violence, and grace as O'Connor was, though he has been much less inclined to self-explanation than was she.

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